A Method for Preparation of Andrographolide from Andrographis paniculata
Andrographis paniculata, the Kalmegh of Ayurveda is an erect annual herb extremely bitter in taste in each and every part of the plant body. The plant is known in north-eastern India as ‘Maha-tita’, literally ‘king of bitters’ and known by various vernacular names. The present invention relates to a method of preparation of more than 98% pure Andrographoloid from Andrographis paniculata analysed by HPLC, from the aerial parts, a method for utilization of annual herb on commercial scale. The invention relates to the use of Andrographolide (active constituent of Kalmegh), for the preparation of a potential pharmaceutical ingredient in commercial scale for the preparation, of a pharmaceutical formulation for treating hepatic disorders.
Sector: Pharmaceuticals
Country: India
Area of Application: Andrographis paniculata is a herbaceous plant in the family Acanthaceae, native to India and Sri Lanka. It is widely cultivated in southern Asia, where it is used to treat infections and some diseases, often being used before antibiotics were created. Mostly the leaves and roots were used for medicinal purposes.
Keywords: Andrographolide , Andrographis peniculata, Extraction, Isolation and purification, HPLC assay.
Advantages: 1). The product is from natural sources , 2.) The whole process of extraction and purification is eco-friendly than synthetic route. 3). Expensive and hazardous chemicals are not in use any where in the process. 4). As the product is from herb used in traditional system of medicines, it is non- toxic. 5). A standardized extraction and purification methodology available.
Environmental aspects: Healthcare
Development Status: Laboratory Model
Legal Protection: Patent
Technical specifications: Free flowing powder with defined contents.
Transfer Terms: Consultancy , Technical Services , Technology Licensing , Others
Target Countries: World Wide
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Address: Amity University Uttar Pradesh Sector-125, Noida
City: Distt Gautam Buddha Nagar
Country: India
Zip/Pin Code: 201303

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