VATIS UPDATE Article

A team of scientists from Russia and Canada has analyzed the effect of space conditions on the protein composition in blood samples of 18 Russian cosmonauts. The results indicated many significant changes in the human body caused by space flight. These changes are intended to help the body adapt and take place in all the major types of human cells, tissues, and organs. Skoltech and MIPT Professor Evgeny Nikolaev initiated this research.

The effects of spaceflight on the human body have been studied actively since the mid-20th century. It is widely known that space conditions influence metabolism, thermoregulation, heart biorhythms, muscle tonus, the respiration system and other physiological aspects of the human body function. However, the molecular mechanisms which drive the physiological changes caused by space flights remain unknown.

Proteins are key players in the adaptive processes in an organism, so the scientists decided to focus on them. To gain a deeper understanding of the changes in human physiology during space travel, the research team quantified concentrations of 125 proteins in the blood plasma of 18 Russian cosmonauts who had been on long-duration missions to the International Space Station. The results have been published in the scientific journal Nature Scientific Reports.